ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ
Kvetnoy I.M., Mironova E.S., Krylova Y.S., Mylnikova A.A., Zubareva T.S., Leont’eva D.O., Polyakova V.O., Petrosyan M.A.
Introduction. Oxidative stress and mitochondrial dysfunction are observed in virtually any disease associated with premature aging. Signaling molecules produced by mitochondria can act as specific targets for the action of pharmacological agents in order to re…
ОБЗОР
Sergeeva E.Y., Fefelova Y.A., Bardezkaya Y.V.
Personalized therapy allows to reveal subtypes of diseases with similar symptoms but various molecular mechanisms of development. Different -omics (genomics, epigenomics, transcriptomics, proteomics ets) are used to divide the diseases into subtypes. Transcrip…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ · pp. 59–64
Dzhobadze G.M., Bruzgina A.A., Kurilova E.A., Tuchina O.P.
The purpose of this study was to determine the influence of transcardial perfusion, as well as social hierarchy in male mice, on the level of gene expression in the cerebral cortex of mice using the example of the proinflammatory cytokine IL-1β. Material and m…