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Molecular Medicine
Found: 230
Ductal adenocarcinoma is the most common type of pancreatic tumors that is notable for its highly aggressive phenotype, difficulties in diagnosis establishing, exceptionally unfavorable prognosis and resistance to standard methods of therapy . The development …
Publications devoted to the role of various representatives of matrix metalloproteinases (MMPs) family and their tissue inhibitors in ovarian cancer in differential diagnostics, prognosis and in the development of new treatment modalities are critically analyz…
To study the correlation of proliferative activity of tumor cells with clinical and morphological parameters and indices of survival rates a retrospective clinical and morphological analysis of 60 cases of localized and metastatic neuroendocrine tumors (NETs) …
In recent years, scientists from different countries are actively discussing the concept of translational medicine and consider it as important area of molecular medicine development. Translational medicine promotes the transfer of discoveries made in basic bi…
There is a growing body of evidence confirming the validity of the concept of cancer stem cells (CSCs). It is becoming increasingly obvious that CSCs, possessing higher tumorigenicity, metastasis-initiating activity and chemoresistance, are a source of tumor g…
Sertoli cells are the primary cells that support developing spermatogenic cells in the seminiferous tubules. Heat treatment induces a reversible change in the Sertoli cells (SC) from the mature differentiated state to an immature-like dedifferentiated state. W…
This review is devoted to availability of investigation of expression of signaling molecules in personalized and predictive medicine. As exemplified in cardio-vascular pathology (hypertonic disease, myocardial infarction), Alzheimer’s disease and chronic obstr…
In autoimmune diabetes mellitus (IDDM), clinical manifestation is typically preceded by several years of latent autoimmune insulitis. The autoimmune process arises only in genetically predisposed people,and is usually provoked by an infectious pathogen. Dagnos…
The effect of PABA in rd10 mice on photoreceptor survival, rhodopsin, blue opsin and red/green opsin contents were quantified in retinal sections using immunofluorescent techniques. The red/green cone opsin content was significantly higher in the retina of rd1…
Dendrimers are routinely synthesized as tuneable nanostructures that may be designed and regulated as a function of their size, shape, surface chemistry and interior void space. Dendrimers are hyperbranched polymers with unique physical and chemical properties…