Found: 67
Research article2013
Maev I.V., Kucheryavyy Yu.A., Andreev D.N., Dicheva D.T.
In the article a review of recent data on the molecular nature of neuroendocrine tumors of the pancreas (pancreatic NETs) is presented. The genetic basis of inherited syndromes associated with the development of pancreatic NETs: multiple endocrine neoplasia ty…
Research article2013
Kulikov E.S., Ogorodova L.M., Freidin M.B., Deev I.A., Selivanova P.A., Fedosenko S.V., Kirillova N.A.
Abstract: This review summarizes the results of studies devoted to identification the dominant mechanisms of formation and persistence of inflammation in severe asthma. According to the latest research, the most likely causal factors and molecules that underli…
Research article2013
Paltsev M.A., Kvetnoy I.M., Ilnitski A.N., Prashchayeu K.I., Kvetnaia T.V., Sovenko G.N., Bessarabov V.I.
The article reviews modern data on the participation of signaling molecules in the pathogenesis of obesity. This review provides the detailed description of the functional morphology of adipose tissue as the major endocrine and immune organ. The imbalance in p…
Research article2012
Kostyushev D.S., Krynskiy S.V., Pozzili P., Filatova G.N., M. von Herrath, Paltsev M.A., Suchkov S.V.
Translational medicine is one of the critical components to overcome the impediments within the objectives of Predictive Preventive and Personalized Medicine. Identification of molecular mechanisms underlying subclinical stages of T1D pathogenesis is a key to …
Research article2012
Prashchayeu K.I., Ilnitski A.N., Bessarabov V.I., Pavlova T.V., Kvetnaya T.V., Bolhovitina O.A., Pozdnyakova N.M.
This article discusses the current level of research on the molecular mechanisms of development and progression of chronic heart failure in elderly and senile age. Described contribute to the pathogenesis of diseases of various signaling molecules and subsyste…
ОБЗОР
Takha E.A., Shuralev E.A., Renaudineau Y., Arleevskaya M.I.
Introduction. Rheumatoid arthritis, like other multifactorial diseases, develops as a result of an inadequate response of a predisposed organism to environmental challenges. Material and methods. A review of the literature on the molecular mechanisms of the ef…
ОБЗОР
Sergeeva E.Y., Fefelova Y.A., Bardezkaya Y.V.
Personalized therapy allows to reveal subtypes of diseases with similar symptoms but various molecular mechanisms of development. Different -omics (genomics, epigenomics, transcriptomics, proteomics ets) are used to divide the diseases into subtypes. Transcrip…