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Molecular Medicine Peer-reviewed scientific journal

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ОБЗОР2026 · pp. 79–86

Molecular mechanisms, pharmacological properties, and applications of PARP inhibitors in ovarian cancer therapy

Relevance. PARP inhibitors (PARPi), have emerged as a significant development in the treatment of high-grade serous ovarian cancer that is associated with mutations in BRCA1/2 and genes of other homologous recombination proteins. These drugs exploit synthetic …

10.29296/24999490-2026-03-11Details ↗
ОБЗОР2026 · pp. 80–88

Current advances in the study of molecular pathogenesis of breast cancer

Introduction. Breast cancer (BC) is a heterogeneous disease that represents a major global health problem. It is the most frequently diagnosed cancer in the world, with the incidence of breast cancer increasing year by year in most countries. The existence of …

10.29296/24999490-2026-01-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

ACTIVATING POINT MUTATION OF BRCA1/2 GENES IN AZERBAIJAN POPULATION

Introduction. Breast cancer is the leading cancer type among woman of Azerbaijan population. Hereditary mutations of the BRCA1/2 genes are considered as high risk for appeared breast and ovarian cancers. In Azerbaijan BRCA1/2-related breast and ovarian cancer …

10.29296/24999490-2019-02-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

ACTUAL ASPECTS OF MOLECULAR-BIOLOGY CLASSIFICATION OF BREAST CANCER

There is represented immunohistochemical and molecular biological characteristic of some histological types of breast cancer. The assessment of molecular biomarkers in breast cancer has two practical results: identification of risk groups, requiring additional…

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