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Molecular Medicine
Found: 9
Introduction. Mitochondrial dysfunction is an important pathogenic mechanism of neurodegeneration, characterized by a progressive structural and functional loss of neurons, leading to heterogeneous clinical and pathological manifestations with subsequent impai…
Introduction. Buccal epithelium (BE), in which cells the expression of signal molecules reflecting the state of homeostasis of the body in normal and pathological conditions is verified, is used as a diagnostic material for a number of diseases in adults. The …
The task of molecular vital diagnosis is to search for peripheral tissues for the verification of biomarkers with the aim of optimization of diagnosis and evaluation of the effectiveness of treatment of socially significant diseases including cardiovascular pa…
Introduction. The current direction of modern medicine is the development of new methods for non-invasive diagnosis of neurodegenerative diseases, in particular, Parkinson's disease. The goal of the investigation was the comparative analysis of α-synuclein and…
Introduction. Alzheimer's disease (AD) is a socially important neurodegenerative disease. The prevalence rate of AD is increasing over recent years. According to the hypothesis concerning AD to be a systematic disease its manifestation can be detected in vario…
Introduction. Significance of chronic parodontitis is determined by not only of the degree of the prevalence rate, severity of the disease, but also by the low efficacy of the treatment and diagnosis at the early stage of disease. Nowadays there are not comple…
Buccal epithelium (BE) is an easily accessible target for molecular diagnosis of various diseases, and non-invasive way to get it is possible. This review summarizes the results of studies indicating a change in the expression of various signaling molecules an…
The expression of signal molecules RON, CD90, CD73, СD64, Pax6, Chx10, RTF1, Oct2, which characterized the status of local and system homeostasis have been verified in the buccal epithelium from women with breast cancer. The most important markers, correlated …
Introduction. Buccal epithelium (BE), in which cells the expression of signal molecules reflecting the state of homeostasis of the body in normal and pathological conditions is verified, is used as a diagnostic material for a number of diseases in adults. The …