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Molecular Medicine Peer-reviewed scientific journal

Found: 10

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 108–115

The Impact of Low Doses of Ethanol on the Taxonomic Composition and Biodiversity of the Microbiota in the Small and Large Intestines of C57Bl6 mice

Alcohol consumption has a detrimental effect on human health and is associated with various pathological changes in the body. In addition to the toxic effect on various tissues and organs, ethanol and its metabolites contribute to persistent changes in the com…

10.29296/24999490-2025-03-14Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2024 · pp. 48–53

TELOMERE LENGTH IN RHESUS MACAQUES WITH VOLUNTARY CHRONIC ETHANOL CONSUMPTION

Introduction. Alcohol abuse is associated with telomere shortening. There is no convincing evidence of a “safe” level of alcohol consumption in this regard. Long-term studies in rodents are not feasible, and clinical trials with the administration of alcohol t…

10.29296/24999490-2024-05-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 56–64

CORRECTION OF ALCOHOL-INDUCED DISORDERS OF WORKING MEMORY WITH NOOPEPT

Introduction. Nootropic drugs are used at all stages in treatment of behavioral disorders associated with alcohol consumption, when the correction of the functions of operational (working) memory and attention contributes to a more adequate processing and assi…

10.29296/24999490-2022-06-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

FABOMOTIZOLE AS MEANS OF PHARMACOLOGICAL CORRECTION OF PRE- AND POSTNATAL DISTURBANCES INDUCED BY PEAT SMOKE POLLUTION, TOBACCO SMOKE, ALCOHOL, HYPERGLYCEMIA AND CYCLOPHOPHAMIDE IN THE DEVELOPMENT OF OFFSPRING OF RATS

Introduction. Influence of environmental hazards on pregnant women or development of pregnancy in presence of pathogenic pathway may lead to miscarriage, teratogenic effects and/or significant abnormalities in physical development, cognitive and behavioral sta…

10.29296/24999490-2020-03-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

COMPARATIVE STUDY OF THE СARDIOPROTECTIVE EFFECT OF TRIMETAZIDINE AND FABOMOTIZOLE HYDROCHLORIDE IN ABSTINENTRATS WITH ESTABLISHED ALCOHOLIC CARDIOMYOPATHY

Introduction. Alcoholic cardiomyopathy is the leading cause of death in persons withchronic alcoholism. This disease is caused by ethanolinduced toxic damage to the heart muscle, which leads to dilated heart failure and the development of the electric myocardi…

10.29296/24999490-2018-03-12Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

CARDIOPROTECTIVE EFFECT OF TRIMETAZIDINE IN RATS WITH ESTABLISHED ALCOHOLIC CARDIOMYOPATHY IN THE ABSTINENCE PERIOD

Aim of the study. To study trimetazidine cardioprotective effects on the translation model of alcoholic cardiomyopathy Materials and methods. Alcoholic cardiomyopathy was reproduced in white mongrel male rats used as the sole source of liquid 10% ethanol solut…

10.29296/24999490-2018-01-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

ABOUT POSSIBILITY OF THE USE OF AFOBAZOL FOR TREATMENT OF ALCOHOLIC CARDIOMYOPATHY AND PREVENTION OF ITS CONCOMITANT COMPLICATIONS

The aim of the study. The proof of afobazole efficacy for treatment and prevention of alcoholic cardiomyopathy and attendant complications using the previously developed translational model. Materials and methods. Alcoholic cardiomyopathy was produced by conti…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

TRANSLATION MODEL OF ALCOHOLIC CARDIOMYOPATHY

The aim of the study – the development of translational models of the alcoholic cardiomyopathy in rats to search and study the action mechanism of new original drugs for the treatment of this pathology. Methods. The complex of echocardiographic, electrophysiol…

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Research article2012

EXPERIMENTAL STUDY OF CRYSTAL STRUCTURES OBSERVED ON THE SURFACEOF THE DENTINE WITH THE USE SCANNING ELECTRON MICROSCOPY

In a series of laboratory experiments on the surface of dentin treated with etching gel – 38% Phosphoric Acid, and exposed to 95% ethanol solution for 30 days at ambient temperature the crystal structures have been found. Three-Dimensional Visualization of the…

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