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Molecular Medicine
Found: 10
Introduction. Cerebrovascular diseases are a heterogeneous group of conditions shaped by the interaction of polygenic susceptibility, rare monogenic variants, vascular remodeling, neuroinflammation, dysregulated hemostasis, and epigenetic reprogramming. Recent…
Introduction. An aortic aneurysm is defined as an irreversible progressive enlargement of the aorta with an increasing risk of rupture, often fatal. It is known that the imbalance of inhibitors and activators of cell matrix proteolysis and the death of smooth …
Introduction. The incidence of eosinophilic esophagitis is 5.31 cases per 100,000 person-years. It is a multifactorial disease with a clear genetic predisposition, specifically involving the expression of the thymic stromal lymphopoietin and IL-33 genes. Eosin…
Introduction. Posttraumatic stress disorder (PTSD) is presented as a systemic multilevel metabolic-immuno-psycho-neurological disorder with genetic predisposition and epigenetic influences, which radically changes the approach to its understanding and treatmen…
Introduction. Neurotoxicity is a common complication of chemotherapy that negatively affects the quality of life of cancer patients. Damage to the nervous system affects both the peripheral nerves (peripheral neuropathy) and the central nervous system (chemo b…
Results. During the analysis of the published pathogenesis of celiac disease (CD) is actively discussed. It is assumed that the change in gluten tolerance is formed under the influence of a number of different factors, including genetic predisposition and envi…
Introduction. Molecular genetic research methods suggest the development of certain forms of pancreatitis and its complications. Aim of the study. Identification of risk factors for the development of acute forms of pancreatitis based on molecular genetic stud…
Introduction. The origin of the genetic predisposition to family adenomatous polyposis is associated with functional disorders of the repair system. The molecular mechanism of this phenomenon is not sufficiently studied and need clarification. The aim of the s…
Preeclampsia is the pregnancy complication characterized by the presence of arterial hypertension and proteinuria. Preeclampsia is the leading cause of maternal and perinatal morbidity and mortality. To date, there are more than 40 advanced theories of etiopat…
Introduction.Study of the influence of molecular and genetic predisposition to forecast neurorehabilitation patients with stroke is of great scientific and practical importance. The aim of the study.Determining the impact of allelic polymorphism Val66Met BDNF …