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Molecular Medicine Peer-reviewed scientific journal

Found: 4

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 33–40

Poisson’s ratio of fluorapatite crystals

Introduction. It is known that in the pathogenesis of caries and non-carious lesions of teeth, an important role is played by enamel resistance, which is determined by numerous factors, among which the structure and physical and mechanical properties of tooth …

10.29296/24999490-2023-06-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

MOLECULAR MODELING, SYNTHESIS AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF MODERN HETEROMEROUS PEPTIDES WITH IMIDAZO[4,5-Е]BENZO[1,2-C;3,4-C’]DIFUROXAN FRAGMENT AS NEW INHIBITORS OF PLATELET AGGREGATION

Introduction. Cardiovascular diseases consistently occupy the first place among causes of death and disability in almost all developed countries. The main importance of this group of diseases have myocardial infarction. One of the causes of myocardial infarcti…

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Research article2014

SEARCH FOR ANTAGONISTS OF NR3C4 RECEPTOR

Introduction. One of the main types of a hormonal therapy in the treatment of the cancer of the prostate gland is the antagonists of the NR3C4 (nuclear receptor subfamily 3, group C, member 4) receptor. It blocks binding of man’s hormones with receptors site, …

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Research article2013

MOLECULAR MODELING, SYNTHESIS AND EVALUATION OF THE BIOLOGICAL ACTIVITYOF NEW GLYCOPROTEIN IIB/IIIA (GPIIB/IIIA) RECEPTOR ANTAGONISTS

We applied software «Algokomb» to perform mathematical modeling of polypeptide molecules of glycoprotein IIb/IIIa (gpIIb/IIIa) receptor antagonists. The modeled compounds have been synthesized accordingly to the protocol of strategy FastMoc 0.25. The structure…

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