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Molecular Medicine Peer-reviewed scientific journal

Found: 10

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 92–100

Morphological features of atherosclerotic plaque: modeling of atherosclerosis after stenting as a model of premature aging

Atherosclerosis and the installation of stents can be considered as a model of premature aging of the body. These processes are associated with chronic inflammation, oxidative stress, loss of cellular function, and impaired regeneration, which makes them a con…

10.29296/24999490-2025-03-12Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2024 · pp. 61–67

Pathomorphological analysis of salinomycin and nanodiamonds efficacy on Lewis lung carcinoma in mice

Relevance. The search for new antitumor drugs and their selective delivery directly to the tumor site is an important task of modern oncology. For these purposes, currently, the use of various nanoparticles as carriers of medicinal substances is of great impor…

10.29296/24999490-2024-06-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 41–46

ROLE OF SIGNALING MOLECULES – FACTORS OF MIGRATION AND ADHESION OF LYMPHOCYTES IN THE PATHOMORPHOSIS OF PULMONARY TUBERCULOMA

Introduction. Tuberculosis is a socially significant disease, which is based on chronic granulomatous inflammation with the formation of fibrosis. The signaling molecules CD44 and ICAM-1 play an important role in the process of migration of immune cells from t…

10.29296/24999490-2023-05-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

MOLECULAR ASPECTS OF CHRONIC ENDOMETRITIS IN FEMALES OF VARIOUS AGE GROUPS

Introduction. Endometritis and elder fertile age are the one of the main reason of infertility. Molecular methods of endometrial investigation have opened new perspectives in diagnostics and evaluation of the efficacy of the management of endometritis Objectiv…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

GE-ASSOSIATED ASPECTS OF THE EXPRESSION OF HUMAN ENDOTHELIAL SIGNAING MOLECULES AND THEIR ROLE IN THE DEVELOPMENT OF CARDIO-VASCULAR PATHOLOGY

Introduction. Age-assosiated endothelial changes are one of the reasons of the development of cardio-vascular pathology. Moreover, molecular mechanisms of human endothelium aging are investigated only slightly. Thus, the problem of pathogenesis of cardio-vascu…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

AGE-RELATED FEATURES OF THE SIGNAL MOLECULES’S PROFILE IN ENDOMETRIUM: PERSPECTIVES FOR DIAGNOSIS OF GYNECOLOGICAL PATHOLOGY

Introduction. Determination of the functional activity of the endometrium at the molecular-cellular level opens new perspectives for diagnosis and correction processes of accelerated aging and pathology of the female’s reproductive system. Objective – learning…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

EXPRESSION OF AORTA ENDOTHELIUM SIGNALING MOLECULES IN AGEING AND ATHEROSCLEROSIS

Introduction. Atherosclerosis proves to be age-dependent and social significant pathology. Knowledge of the role of signaling molecules in its development, and the elaboration on this basis molecular markers of restenosis after stenting of arteries remains to …

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Research article2013

CARDIOPROTECTIVE EFFECTS OF AFOBAZOL IN ANIMALS WITH CHRONIC MYOCARDIAL ISCHEMIA

Morphometric studies of the median transverse sections of rat hearts, performed on 28th day after coronary artery ligation, showed that as a result of myocardial infarction the pronounced postinfarction remodelling of the left ventricle of the heart was observ…

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