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Molecular Medicine Peer-reviewed scientific journal

Found: 2

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

MOLECULAR MODELING, SYNTHESIS AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF MODERN HETEROMEROUS PEPTIDES WITH IMIDAZO[4,5-Е]BENZO[1,2-C;3,4-C’]DIFUROXAN FRAGMENT AS NEW INHIBITORS OF PLATELET AGGREGATION

Introduction. Cardiovascular diseases consistently occupy the first place among causes of death and disability in almost all developed countries. The main importance of this group of diseases have myocardial infarction. One of the causes of myocardial infarcti…

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Research article2013

MOLECULAR MODELING, SYNTHESIS AND EVALUATION OF THE BIOLOGICAL ACTIVITYOF NEW GLYCOPROTEIN IIB/IIIA (GPIIB/IIIA) RECEPTOR ANTAGONISTS

We applied software «Algokomb» to perform mathematical modeling of polypeptide molecules of glycoprotein IIb/IIIa (gpIIb/IIIa) receptor antagonists. The modeled compounds have been synthesized accordingly to the protocol of strategy FastMoc 0.25. The structure…

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