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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

SEX HORMONES AS REGULATORS OF THE LEVEL OF GROWTH FACTORS IN TUMOR TISSUES IN POLYNEOPLASIA OF FEMALE REPRODUCTIVE ORGANS

Frantsiyants E.M., Moiseenko T.I., Vereskunova M.I., Adamyan M.L., Chernikova N.V., Gurnak V.V., Boiko K.P.

Introduction. Sex hormones are known to influence on synthesis of growth factors in breast and uterus tumors, but their correlation in polyneoplasias is poorly studied. The aim of the study. The analyze local steroidogenesis, synthesis of growth factors and th…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

INSULIN-LIKE GROWTH FACTORS AND SEX HORMONES IN TUMOR TISSUE IN POLYNEOPLASIAS OF FEMALE REPRODUCTIVE ORGANS

Frantsiyants E.M., Komarova E.F., Moiseenko T.I., Vereskunova M.I., Adamyan M.L., Chernikova N.V., Gurnak V.V., Boiko K.P.

Introduction. IGF-1R in breast cancer tumor tissue was shown to be expressed in large quantities in comparison with benign tumor or normal breast tissue. At the same time, IGF-1 stimulates proliferation of normal and tumor breast cells. The aim of the study. T…

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