This website is intended for professionals in medicine and healthcare. By selecting “Confirm”, I declare that I am a member of this professional audience. I also agree to the publisher’s rules for using its information resource. Publisher’s resource rules (Russian)
Molecular Medicine
Found: 16
Relevance. Ectopic secretion, which occurs in the early stages of tumor development, is not only one of the first signs of a neoplasm, but can also indicate the severity of the oncological process. Purpose of the study: To evaluate the possibility of using the…
The review is devoted to the analysis of modern ideas about the molecular mechanisms of tumor transformation in tuberculosis; signal molecules are described, which may be biomarkers and targets for optimizing personalized diagnosis and targeted therapy of the …
Introduction. Buccal epithelium (BE), in which cells the expression of signal molecules reflecting the state of homeostasis of the body in normal and pathological conditions is verified, is used as a diagnostic material for a number of diseases in adults. The …
Introduction. Sarcoidosis is a systemic granulomatous disease of unknown etiology, which leads to disruption of the human respiratory system and can lead to damage to other systems. In clinical practice, doctors often run into difficulties in differentiating s…
Introduction. Leiomyomas also called fibroids, is the most common benign gynecological tumor in premenopausal women. The complex pathogenesis shows multiple biogenetical and multifactorial aspects to influence the etiology and growth of leiomyomas. A clinical …
Introduction. The Alzheimer disease (AD) is the socially important neurodegenerative disease. The promising way of the early lifetime diagnosis of the AD is the investigation of the expression of signal molecules by cells in a cerebrospinal fluid, blood lympho…
Introduction. The article is devoted to the actual medical and social problem of modern reproductive medicine – new approaches to improve and regenerate the implantation susceptibility of the endometrium in infertility. Currently, in addition to traditional ho…
Introduction. The investigation of molecular and cellular mechanisms of atherosclerosis and the development of restenosis and the possibility of the regulation of these processes by short peptides opens new perspectives for the delivery of vasoprotective prepa…
Introduction. The assessment of placental dysfunction in clinical practice remains to be subject of debates, the search of sustaining morphological markers continues. The aim of the study was to find the correlation between the expression of vimentin and place…
Introduction. Significance of chronic parodontitis is determined by not only of the degree of the prevalence rate, severity of the disease, but also by the low efficacy of the treatment and diagnosis at the early stage of disease. Nowadays there are not comple…
Introduction. Age-assosiated endothelial changes are one of the reasons of the development of cardio-vascular pathology. Moreover, molecular mechanisms of human endothelium aging are investigated only slightly. Thus, the problem of pathogenesis of cardio-vascu…
Introduction. Determination of the functional activity of the endometrium at the molecular-cellular level opens new perspectives for diagnosis and correction processes of accelerated aging and pathology of the female’s reproductive system. Objective – learning…
Introduction. Atherosclerosis proves to be age-dependent and social significant pathology. Knowledge of the role of signaling molecules in its development, and the elaboration on this basis molecular markers of restenosis after stenting of arteries remains to …
The article reviews modern data on the participation of signaling molecules in the pathogenesis of obesity. This review provides the detailed description of the functional morphology of adipose tissue as the major endocrine and immune organ. The imbalance in p…
The expression of signal molecules RON, CD90, CD73, СD64, Pax6, Chx10, RTF1, Oct2, which characterized the status of local and system homeostasis have been verified in the buccal epithelium from women with breast cancer. The most important markers, correlated …
Introduction. Buccal epithelium (BE), in which cells the expression of signal molecules reflecting the state of homeostasis of the body in normal and pathological conditions is verified, is used as a diagnostic material for a number of diseases in adults. The …