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Molecular Medicine
Found: 4
The aim of this review is to systematize current knowledge on the role of selenium in biochemical processes and in the development of diseases associated with its deficiency or excess. Material and methods. A comprehensive search and analysis of publications f…
Introduction. Short peptides are considered a promising class of geroprotective agents capable of modifying key molecular mechanisms of aging, from epigenetic regulation of gene expression to maintenance of neuroendocrine and antioxidant homeostasis. Laborator…
Introduction. Alcohol abuse is associated with telomere shortening. There is no convincing evidence of a “safe” level of alcohol consumption in this regard. Long-term studies in rodents are not feasible, and clinical trials with the administration of alcohol t…
Telomerase catalytic subunit hTERT is tightly regulated both at the transcriptional and posttranscriptional levels. One of the regulatory mechanisms is its mRNA alternative splicing. Only full-length form has catalytic activity and the ability to elongate telo…