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Molecular Medicine
Found: 3
Introduction. An aortic aneurysm is defined as an irreversible progressive enlargement of the aorta with an increasing risk of rupture, often fatal. It is known that the imbalance of inhibitors and activators of cell matrix proteolysis and the death of smooth …
Introduction. The ACTA2 gene encodes α-actin in aortic smooth muscle cells, and its mutations may cause thoracic aortic aneurysms. Analysis of ACTA2 polymorphism can be used in a complex risk assessment of non-familial thoracic aortic aneurysms. The aim of the…
The etiologic factors, features of pathogenesis and pathomorphology of thoracic and abdominal aortic aneurysms are considered in review. The morphologic and biologic features of the wall of thoracic aneurysms in Marfan's disease, Ehlers-Danlos, Loeys-Dietz, Tu…