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Molecular Medicine Peer-reviewed scientific journal

Found: 11

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 53–58

Modern anticoagulants in the treatment and prevention of thrombotic complications in patients with Hodgkin’s lymphoma

Introduction. Cancer patients have a high risk of developing venous thromboembolic complications, which worsen the outcomes of antitumor treatment and are the second leading cause of death after cancer progression. Objectives – to assess the effect of modern a…

10.29296/24999490-2026-03-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 35–42

Eosinophils are predictors of susceptibility to thrombosis and severe course of Covid-19 in various types of therapy

The creation by COVID-19 of methods for prophylactic of these complications as blood hypercoagulation, leading to thrombosis and polyorganic insufficiency, is an urgent task of modern biology and medicine. The aim of the study was to develop the simple methods…

10.29296/24999490-2022-04-06Details ↗
ОБЗОР2022 · pp. 9–15

SASP OF ENDOTHELIUM AND VASCULAR SMOOTH MUSCLE CELLS: ROLE IN THE PATHOGENESIS AND THERAPY OF ATHEROSCLEROSIS

The senescence-associated secretory phenotype (SASP) is one of the causes of age-associated diseases, including atherosclerosis. The purpose of the review is to analyze data on the role of SASP cells of the cardiovascular system in the pathogenesis and pharmac…

10.29296/24999490-2022-04-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

POLYMORPHISM AND SYNERGISM OF THE HEMOSTASIS SYSTEM GENES IN PATHOGENESIS OF INFECTIVE ENDOCARDITIS

Introduction. The genetically determined tendency of patients to thrombosis may be one of the etiopathophysiological factors of the infective endocarditis (IE). Aim. А search for variants of genes and their combinations in the hemostatic system, the carriage o…

10.29296/24999490-2019-04-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

GENETIC POLYMORPHISM OF F2, F5 AND VKORC1 IN POPULATIONS OF BURYATS, TELEUTS AND RUSSIANS OF THE EASTERN SIBERIA

Introduction. The study of the prevalence of genetic risk factors for thrombosis-associated diseases in the indigenous population of Siberia is an important issue in current medicine. The aim of the study. The aim of this work is to study the allele frequencie…

10.29296/24999490-2018-03-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

THE POSSIBILITY OF THE ANGIOGENESIS IN TISSUES REMOTE FROM THE PLACE OF THE MULTIPOTENT MESENCHYMAL STROMAL CELL INJECTION

Introduction. The use of cell technologies has particular effectiveness in the correction of the experimental venous thrombosis and acute local obstruction to the blood outflow. Autologic multipotent mesenchymal stromal cells of a bone marrow origin (AMMSCBMO)…

10.29296/24999490-2018-03-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

CLINICAL SIGNIFICANCE OF GENE CYP2C19 POLYMORPHISM IN STEMI PATIENTS (DATA FROM THE KEMEROVO REGISTRY OF THE ACUTE CORONARY SYNDROME)

Aim is to evaluate distribution and clinical significance of gene CYP2C19 polymorfism in ST-segment elevation myocardial infarction (STEMI) patients. Materials and methods. A total of 159 patients were encluded in this study. All of them underwent primary PCI.…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

PRENATAL HYPERHOMOCYSTEINEMIA AND OXIDATIVE STRESS PROFILE IN THE RAT OFFSPRING

Introduction. Oxidative stress is developed as a result of imbalance between the generation of reactive oxygen species and activity of the antioxidant defence system. This in turn results in profound changes in metabolism of lipids, proteins and nucleic acids,…

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Research article2013

ABNORMALITIES OF HEMOSTASIS AND THEIR PREVENTION IN CANCER PATIENTS

Venous thromboembolism (VTE) is a frequent complication associated with increased mortality in cancer patients. The basic role in pathogenesis of thrombotic complication in cancer patients is played by changes in the hemostatic system caused by the tumor itsel…

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