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MODIFICATION OF PROTEIN MOLECULES UNDER ENDOGENOUS INTOXICATIONAS A RISK FACTOR OF CHRONIC METABOLIC DISEASES

Yurieva E.A., Sukhorukov V.S., Tsaregorodtsev A.D., Vozdvizhenskaya E.S., Kharabadze M.N., Novikova N.N., Kovalchuk M.V.

The enhancement of ligand properties of protein molecules treated by toxic reagents has been revealed in model experiments in vitro on ordered protein films. In patients with endogenous intoxication caused by metabolic disorders there were also detected protei…