Table of contents
ОБЗОРЫ
METABOLIC RESEARCH FROM THE STANDPOINT OF PERSONALIZED MEDICINE
One of the most important tasks of modern medicine is to recognize diseases at the preclinical stage, as well as to assess their development risks and their possible prevention. This dictates the need to use new, modern technologies aimed at the early detectio…
THE USE OF MESENCHYMAL STEM CELLS IN THE TREATMENT OF OSTEOARTHRITIS
The purpose of the study was to analyze literature data on the use of mesenchymal stem cells as a conservative treatment of osteoarthritis. Material and methods. Literature search was carried out using keywords: traumatology, orthopedics, mesenchymal stem cell…
MODERN METHOD OF SARS-CоV-2 COMBAT
Relevance: COVID-19 is the accepted name for an acute respiratory disease caused by the SARS-CoV-2 coronavirus. The suddenness, speed of spread, severity, and high lethality of COVID-19 have led many of the drugs used in the early stages of a pandemic to be ba…
PREMATURE AGING (INFLAMAGING) AND DISEASES OF THE FEMALE REPRODUCTIVE SYSTEM
Relevance. The review is devoted to the issue of aging and the relationship of the molecular processes of aging with the pathology of the reproductive system The aim of the study was to review the current understanding of aging, the mechanisms and role in the …
ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ
STUDY OF THE RELATIONSHIP OF IRON CONCENTRATION WITH THE FERRITIN AND TRANSFERRIN IN BLOOD SERUM
Introduction. Iron is one of the main elements for the vital activity of the body. Iron deficiency leads to the development of iron deficiency anemia, one of the most common diseases in the Russian Federation; excess iron induces oxidative stress. In this way,…
THE EFFECT OF TUBERCULOSIS ON THE COURSE OF LUNG CARCINOMA IN THE EXPERIMENT
Introduction. One of the problems of modern medicine is the low efficiency of treatment of patients with a coexistence of lung cancer and active tuberculosis. Optimal treatment regimens for coexistence pathology have not been developed at present. In recent ye…
РЕТРАГИРОВАНА / RETRACTED FEATURES OF EXPERIMENTAL OSTEOARTHROSIS CAUSED BY DEXAMETHASONE AND TALC
Introduction. An experimental study of the pathogenetic mechanisms of the development of inflammatory-destructive changes in the joints in animal models was carried out in order to develop new diagnostic strategies for further implementation of the results obt…
THE LEVEL OF IMMUNE CHECKPOINT CO-INHIBITORS IN TUMOR TISSUE IN PATIENTS WITH COLON TUMOR
Introduction. A high level of checkpoint co-inhibitors in the tumor microenvironment plays an important role in inhibiting the local immune response, which contributes to the growth and progression of cancer. The aim of the study. We aimed to determine immune …
COMBINED EFFECT OF POLYPEPTIDE COMPLEXES ON THE DEVELOPMENT OF ORGANOTYPIC CULTURE OF RAT TISSUES
Introduction. The formation of effective bioregulators for the maintenance of the basic physiological functions, so as polypeptide complexes (PPCs), is one of the actual task of modern biology and medicine. Purpose of study. Effect of combination of polypeptid…