THE ROLE OF SIGNALING MOLECULES IN PATHOGENESIS OF GASTROINTESTINAL TRACT DISEASES:OPTIMIZATION OF DIAGNOSTICS AND TARGET THERAPY

The review is devoted to the role of some signaling molecules produced by neuroendocrine and immune cells of the gastrointestinal
tract (GIT) in the pathogenesis of the diseases of the digestive system. Special attention is paid to the key signaling molecules that provide
local interactions between neuroimmunoendocrine cells and are considered as potential biomarkers. The determination of expression
of such potential biomarkers should permit to optimize the diagnosis and choice of effective target therapy of specific gastrointestinal
diseases.

A.N. Ailamazyan
The Research Institute of Obstetrics and Gynecology named after D.O. Ott, St. Petersburg, The Saint Petersburg State Medical University named after I.P. Pavlov, St. Petersburg