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Molecular Medicine Peer-reviewed scientific journal

Molecular Medicine

CLINICAL SIGNIFICANCE OF EPIDERMAL GROWTH FACTORS AND SEX STEROIDS IN ENDOMETRIAL TUMORS

Azhigova R.R., Kuznetsova O.M., Galdava D.E., Dvorova E.K., Laktionov K.P., Berezov T.T.

Authors and affiliations

R.R. Azhigova (1), O.M. Kuznetsova (1), D.E. Galdava (2), E.K. Dvorova (2), K.P. Laktionov (2), T.T. Berezov (1)
1 -Peoples’ Friendship University of Russia, Moscow
2 -N.N. Blokhin Russian Cancer Research Center, Moscow

Published
2013

Abstract

The study data of the epidermal growth factor receptors(EGFR), estrogen and progesterone receptors(ER, PR) in the endometrial
tumors in 125 patients are presented. EGFR have been detected in 40% of tumors. The EGFR–RP+ER+ tumors were detected most frequently
(48,8%) and EGFR+ER+PR+ (30,4%) were identified less often. The frequency of detection of EGFR in the tumor being more informative
than its level in patients with endometrial cancer decreased in cases of unfavorable clinical and morphological characteristics of the disease.
The relationship between the expression of EGFR, ER and PR with a prognosis of endometrial cancer is discussed

Keywords

Authors and affiliations

R.R. Azhigova (1), O.M. Kuznetsova (1), D.E. Galdava (2), E.K. Dvorova (2), K.P. Laktionov (2), T.T. Berezov (1)
1 -Peoples’ Friendship University of Russia, Moscow
2 -N.N. Blokhin Russian Cancer Research Center, Moscow

How to cite

Azhigova R.R., Kuznetsova O.M., Galdava D.E., Dvorova E.K., Laktionov K.P., Berezov T.T. (2013). CLINICAL SIGNIFICANCE OF EPIDERMAL GROWTH FACTORS AND SEX STEROIDS IN ENDOMETRIAL TUMORS. Molecular Medicine, (6).

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