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Molecular Medicine Peer-reviewed scientific journal

Found: 28

ОБЗОР2018

A ROLE OF THE NEUROPEPTIDE GALANIN IN THE REGULATION OF BIOLOGICAL FUNCTIONS OF THE HUMAN ORGANISM IN NORMAL AND PATHOLOGIC CONDITIONS

The neuropeptide galanin (Gal) is widely distributed as well in central and peripheral nervous system, as in other organs and tissues of humans and animals. Its pleotropic effect is due to an activation or inhibition of galanin specific receptors – GalR1, GalR…

10.29296/24999490-2018-03-01Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

G276T ADIPONECTIN GENE POLYMORPHISM IN DEVELOPMENT OF OBESITY AND OBESITY-RELATED DISEASES IN KYRGYZ POPULATION

The aim of this work was to study the relationship between adiponectin gene polymorphisms G276T with obesity and obesity-related diseases in the Kyrgyz population. Material and methods. We genotyped 288 Kyrgyz subjects (143 women and 145 men; age range: 30–75 …

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

GENERAL AND SPECIFIC IN THE GENOME OF PATIENTS WITH TYPE 1 AND TYPE 2 DIABETES

Introduction. Diabetes mellitus type 1 and type 2 are having a number similar etiological factors and certain resemblance in the mechanisms of the disease. Therefore it is important to try to estimate the role of common genetic component in the genesis and for…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

PREDICTION THE RISK OF ISCHEMIC STROKE ON THE BASE ON GENETIC [APOE (Ε2, Ε3, Ε4), ACE (I / D), MTHFR (677S> T)] AND NON-GENETIC FACTORS WITH THE USE OF MODERN METHODS OF THE THEORY OF RECOGNITION BY PRECEDENTS

Introduction. Ischemic stroke (IS) is a multifactorial disease, resulting from a complex interaction of genetic and environmental factors. Individual cause of the disease, multiple factors and symptoms require advanced mathematical methods of predicting IS ris…

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Research article2014

FREE RADICAL OXIDATION OF PROTEINS AND LIPIDS IN ADIPOCYTES UNDER CONDITIONS OF OXIDATIVE STRESS

Introduction. According to the current understanding, oxidative stress plays a key role in the mechanisms of diabetes mellitus of types 1 and 2 emergence and development of its complications; formation of oxidative stress is accompanied by defective uptake of …

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Research article2012

MOLECULAR AND CELLULAR TARGETS AS THE BASISOF PRECLINICAL DIAGNOSIS OF TYPE 1 DIABETES: PROBLEMS AND PROSPECTS

In autoimmune diabetes mellitus (IDDM), clinical manifestation is typically preceded by several years of latent autoimmune insulitis. The autoimmune process arises only in genetically predisposed people,and is usually provoked by an infectious pathogen. Dagnos…

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