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Molecular Medicine Peer-reviewed scientific journal

Found: 63

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ

MITOCHONDRIA – INTRACELLULAR TARGETS OF GEROPROTECTIVE EFFECT OF V007

Introduction. Oxidative stress and mitochondrial dysfunction are observed in virtually any disease associated with premature aging. Signaling molecules produced by mitochondria can act as specific targets for the action of pharmacological agents in order to re…

10.29296/24999490-2022-01-04Details ↗
ОБЗОР

PROVOCATION OF OXIDATIVE STRESS BY HEAVY METALS AS A POSSIBLE TRIGGER FACTOR IN THE DEVELOPMENT OF RHEUMATOID ARTHRITIS

Introduction. Rheumatoid arthritis, like other multifactorial diseases, develops as a result of an inadequate response of a predisposed organism to environmental challenges. Material and methods. A review of the literature on the molecular mechanisms of the ef…

10.29296/24999490-2022-01-03Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ · pp. 59–64

ASSESSMENT OF INTERLEUKIN-1β EXPRESSION LEVEL IN THE CEREBRAL CORTEX OF MICE IN A MODEL OF POST-TRAUMATIC STRESS DISORDER: METHODOLOGICAL RECOMMENDATIONS

The purpose of this study was to determine the influence of transcardial perfusion, as well as social hierarchy in male mice, on the level of gene expression in the cerebral cortex of mice using the example of the proinflammatory cytokine IL-1β. Material and m…

10.29296/24999490-2023-05-09Details ↗

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