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Molecular Medicine
Found: 130
Summary. Polymorphism of cytokine genes IL-2 (T330G), IL-10 (S819T) and IL10 (G1082A) in chronic viral hepatitis C. The analysis of the frequency of occurrence T330G polymorphism in the promoter region of the gene IL-2, S819T and G1082A promoter region of IL-1…
Early diagnosis of ovarian cancer (OC) remains to be the actual problem in modern oncology due to the high mortality rate, asymptomatic course of the disease in the early stages and its aggressiveness. The aim was to study the genetic polymorphism of pathogene…
Head and neck squamous cell carcinoma is one of the aggressive forms of cancer, which often presents at advanced stages, being associated with poor prognosis and low survival rates. Therefore, the delivery new biomarkers for early cancer detection and predicti…
Diffuse large B-cell lymphoma is the most common lymphoma worldwide. Both morphologically and prognostically it represents a diverse spectrum of disease. Non-Hodgkin lymphoma of bone comprises approximately 7% of malignant bone tumors, 5% of extranodal lymphom…
With the purpose to determine the content of apoptotic lymphocytes of venous blood in norm and pathology there were examined 40 primary donors of blood, 14 patients with closed abdominal trauma complicated by acute blood loss of at least 30% of circulating blo…
The Use of the technique of contrast enhancement in spiral computed tomography (SCT) allows us to study the peculiarities of hemodynamics in the tumor tissue and thus facilitates the differential diagnosis. Сomparison of SKT data with the results of morphologi…
In autoimmune diabetes mellitus (IDDM), clinical manifestation is typically preceded by several years of latent autoimmune insulitis. The autoimmune process arises only in genetically predisposed people,and is usually provoked by an infectious pathogen. Dagnos…
Translational medicine is one of the critical components to overcome the impediments within the objectives of Predictive Preventive and Personalized Medicine. Identification of molecular mechanisms underlying subclinical stages of T1D pathogenesis is a key to …
There are a many applications of biosensors in biochemical analysis at different regions of human life at present time which caused by their high sensitivity, performance speed and small sizes in contrast to traditional methods of analysis. Optical biosensors …
Personalized therapy allows to reveal subtypes of diseases with similar symptoms but various molecular mechanisms of development. Different -omics (genomics, epigenomics, transcriptomics, proteomics ets) are used to divide the diseases into subtypes. Transcrip…