Table of contents
ОБЗОРЫ
NEW LONG NON-CODING RNAS IN LUNG CANCER ONCOGENESIS
This review is devoted to summarizing the available data on the expression of long non-coding RNAs (lncRNAs) in lung cancer cells and tissues, their role in tumorigenesis, association with clinical and morphological characteristics and disease prognosis. The p…
CONNEXINS: ROLE IN INTERCELLULAR INTERACTIONS IN NORMAL AND IN PATHOLOGY OF THE RESPIRATORY SYSTEM
Relevance. The review is devoted to the analysis of modern ideas about the functional role of connexins in intercellular interactions, their participation in maintaining cellular and tissue homeostasis and in the pathogenesis of diseases of the respiratory sys…
ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ
EXPRESSION OF KISSPEPTIN IN LUNG CARCINOMA AS AN INDICATOR OF TUMOR PROGRESSION
Introduction. Lung carcinoma is one of the most common cancers and the most likely cause of cancer mortality in the world. The use of the IHC method to determine the immunophenotype of tumor cells greatly facilitates the differential diagnostic search, allows …
USE OF MESENCHYMAL STEM CELLS IN COMPLEX TREATMENT OF DRUG-RESISTANT RENAL TUBERCULOSIS (EXPERIMENTAL STUDY WITH MORPHOLOGICAL CONTROL)
Introduction. The use of mesenchymal stem cells (MSCs) is recognized as a promising direction for the treatment of diseases with a predominance of inflammation and sclerosis in the pathogenesis, which includes nephrotuberculosis (NT). Target. Studying the effe…
STUDYING THE RELATIONSHIP OF COPPER AND ZINC CONCENTRATIONS IN BLOOD SERUM WITH INFLAMMATION MARKERS
Introduction. According to modern concepts, the inflammatory process is one of the key links in the development of cardiovascular, autoimmune, neurological, oncological diseases, as well as metabolic syndrome, complications of diabetes mellitus, and pathologie…
ROLE OF SIGNALING MOLECULES – FACTORS OF MIGRATION AND ADHESION OF LYMPHOCYTES IN THE PATHOMORPHOSIS OF PULMONARY TUBERCULOMA
Introduction. Tuberculosis is a socially significant disease, which is based on chronic granulomatous inflammation with the formation of fibrosis. The signaling molecules CD44 and ICAM-1 play an important role in the process of migration of immune cells from t…
PROLIFEROTROPIC EFFECT OF COMBINATIONS OF SHORT PEPTIDES AND ENCODED AMINO ACIDS IN ORGANOTYPIC CULTURE OF TISSUE OF DIFFERENT GENESIS
Introduction. An urgent problem in biology and medicine is the identification of biologically active molecules that affect the cellular processes of proliferation and apoptosis in various tissues of the body. Purpose of the study. The purpose of this study was…
LOCAL PRODUCTION OF NEUROTROPHIC FACTORS UNDER THE INFLUENCE OF FRACTAL STIMULATION PHOTOTHERAPY ON THE RETINA OF RABBITS
Introduction. Recently, a new approach to visual response has been discussed, based on the use of optical signals of a heavy structure, manifested by fractal dynamics. However, the molecular mechanisms of action of fractal phototherapy (FF) have not been studi…