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Molecular Medicine Peer-reviewed scientific journal

Molecular Medicine

Articles

ОБЗОР2025 · pp. 64–74

The Role of P2X7 Receptors in the Pathogenesis of Depression and Autism Spectrum Disorders

Introduction. Purinergic signaling pathways in brain cells can play an important role both in physiological conditions and in depression and autism spectrum disorders. The purpose of this literature review was a systematic analysis of information in the modern…

10.29296/24999490-2025-04-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 101–107

Effect of the S-nitrosoglutathione nitric oxide donor on the relative amount of P-selectin in vitro

Introduction. Studying the effect of the nitric oxide (II) donor, S-nitrosoglutathione, on the relative amount of selectin P in HUVEC cell lysates in vitro may contribute to fundamental understanding of the effect of the nitric oxide system on the adhesive fun…

10.29296/24999490-2025-03-13Details ↗
ОБЗОР2025 · pp. 19–29

Molecular mechanisms and pharmacogenetic determinants of II–III generation antihistamines efficacy in allergic bronchial asthma: personalized therapy prospects

Introduction. Allergic bronchial asthma (BA) is accompanied by activation of histamine H1/H4 receptors and variable response to antihistamines. The aim of this review is to analyze the molecular mechanisms of action of second- and third-generation antihistamin…

10.29296/24999490-2025-03-03Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 56–61

Molecular genetic features of iron deficiency anemia phenotypes

Relevance. Iron deficiency anemia is a disease present all over the world and maintaining a high incidence rate of both general and primary morbidity despite various options for correction and prevention of this pathology. Molecular genotyping opens up new pos…

10.29296/24999490-2025-03-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 77–85

Is the progression of tuberculosis possible against the background of antitumor therapy for lung cancer? Results of an experimental study

Aim of the study. The possibility of using antitumor drugs against the background of active tuberculosis is an unresolved problem of modern medicine. The aim of the experimental study was to study the course of tuberculosis infection against the background of …

10.29296/24999490-2025-03-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 108–115

The Impact of Low Doses of Ethanol on the Taxonomic Composition and Biodiversity of the Microbiota in the Small and Large Intestines of C57Bl6 mice

Alcohol consumption has a detrimental effect on human health and is associated with various pathological changes in the body. In addition to the toxic effect on various tissues and organs, ethanol and its metabolites contribute to persistent changes in the com…

10.29296/24999490-2025-03-14Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 86–91

Characteristics of the gut microbiota of patients with dyspepsia

Introduction: Studying the relationship between functional dyspepsia and gut microbiota will provide insight into the role of individual microorganisms and their metabolic products in the development of this pathology. The aim of the study was to analyze the m…

10.29296/24999490-2025-03-11Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 68–76

Features of local synthesis of neurotrophic factors under the influence of fractal stimulation phototherapy in a model of retinal pigment epithelium atrophy on rabbit

Introduction. It is assumed that in degenerative diseases of the retina, photostimulation with fractal dynamics signals activates neuroplasticity, increasing the effectiveness of visual rehabilitation. Previously, we demonstrated the positive effect of fractal…

10.29296/24999490-2025-03-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 92–100

Morphological features of atherosclerotic plaque: modeling of atherosclerosis after stenting as a model of premature aging

Atherosclerosis and the installation of stents can be considered as a model of premature aging of the body. These processes are associated with chronic inflammation, oxidative stress, loss of cellular function, and impaired regeneration, which makes them a con…

10.29296/24999490-2025-03-12Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 39–47

Ways to increase freedom from DOAC-dependent complications in elderly patients with polypharmacy and chronic kidney disease: molecular and genetic aspects

Introduction. Thanks to advances in modern medicine, it has been possible to significantly increase life expectancy. With the high effectiveness of methods for diagnosing and treating many chronic pathologies, a sharp increase in the number of elderly patients…

10.29296/24999490-2025-03-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 48–55

Molecular mechanisms of skin biorevitalization: expression of signaling molecules under the action of trehalose-containing gel

Introduction: Biorevitalization is a modern method of injection cosmetology aimed at correcting age-related skin changes by introducing hyaluronic acid (HA) and additional biologically active components. The hyaluronic gel for microimplantation and mesotherapy…

10.29296/24999490-2025-03-06Details ↗

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