This website is intended for professionals in medicine and healthcare. By selecting “Confirm”, I declare that I am a member of this professional audience. I also agree to the publisher’s rules for using its information resource. Publisher’s resource rules (Russian)
Molecular Medicine
The literature review provides information on the molecular biology of low-grade malignancy gliomas (LGMG) in children and adolescents. The data on specific genetic aberrations in pilocytic astrocytoma, pleomorphic xantoastrocytoma, subependimal giant cell ast…
The problem of the treatment of hyperplastic diseases of endometrium currently remains to be a matter of interest. Existing methods of hormone therapy fail to differ in high efficacy. Authors tried to find out reasons for the lack of success of hormonal manage…
Introduction. Binding of the human immunodeficiency virus (HIV) envelope gp120 glycoprotein to CD4 and CCR5 receptors on the cell membrane initiates the viral entry process. Simultaneous expression of these two receptors has been observed on T-lymphocytes, mon…
Introduction. Short-term and long-term memory impairments are the main symptoms of several socially important neurodegenerative disorders, such as Alzheimer disease. For this purpose the pharmacological enhancement of short-term memory is of great interest. No…
Introduction. SLCO1B1 encodes the organic anion-transporting polypeptide which has been shown to regulate the hepatic uptake of statins. SLCO1B1*5 genetic variant is associated with the high risk for statin-induced myopathy in patients with statins therapy. Ai…
Introduction. Endometritis and elder fertile age are the one of the main reason of infertility. Molecular methods of endometrial investigation have opened new perspectives in diagnostics and evaluation of the efficacy of the management of endometritis Objectiv…
Introduction. The influence of widespread, often long-lasting infections like herpes simplex virus (HSV), cytomegalovirus (CMV) and chlamydia infections on endocrine profile in organs of reproductive system and the role of infections in pathogenesis of uterine…
Introduction. Immunologic microenvironment of malignant tumors is likely to be significant in «tumor-host» interaction. The aim of the study. Сomparative analysis of systemic and local factors of cellular and humoral immunity in patients with ascitic forms of …
Introduction. Study of growth factors content in tumors of different localizations and assessment of their probable correlation with the main clinical and morphological characteristics are relevant nowadays. Products of expression of the viral genome – E7 and …
The neuropeptide galanin (Gal) is widely distributed as well in central and peripheral nervous system, as in other organs and tissues of humans and animals. Its pleotropic effect is due to an activation or inhibition of galanin specific receptors – GalR1, GalR…
Introduction. Endometrial hyperplasia represents a chronic progressive disease characterized by high prevalence among women in older age groups. The aim of the study. To study the involvement of combinations of candidate genes in the formation of hyperplastic …
This article reviews loop-mediated isothermal amplification (LAMP) technique that since its invention in 2000 has gradually become one of the most popular isothermal amplification technologies. In this paper, we described the mechanism of LAMP reaction, differ…