Table of contents
Articles
PARAAMINOBENZOIC ACID IMPROVES SURVIVAL OF PHOTORECEPTORS IN rd10 MICE MODEL
The effect of PABA in rd10 mice on photoreceptor survival, rhodopsin, blue opsin and red/green opsin contents were quantified in retinal sections using immunofluorescent techniques. The red/green cone opsin content was significantly higher in the retina of rd1…
EXPERIMENTAL STUDY OF CRYSTAL STRUCTURES OBSERVED ON THE SURFACEOF THE DENTINE WITH THE USE SCANNING ELECTRON MICROSCOPY
In a series of laboratory experiments on the surface of dentin treated with etching gel – 38% Phosphoric Acid, and exposed to 95% ethanol solution for 30 days at ambient temperature the crystal structures have been found. Three-Dimensional Visualization of the…
VASCULAR TROPIC SIGNALING MOLECULES EXPRESSION IN THE PLACENTALTISSUE SAMPLES FROM PUERPERAE WITH GESTATIONAL DIABETES MELLITUS
The assessment of vascular endothelial growth factor (VEGF) and endotelial NO – synthase (eNOS) expression levels in placental tissue samples obtained from pregnant females with gestational diabetes mellitus (GDM) has been performed. The highest level of these…
EXPRESSION OF GLUCOSE TRANSPORTERS ON PLACENTAL VILI THROUGH GESTATION
Immunohystochemical examination revealed increasing of GLUT1 and decreasing of GLUT3 expression through gestation. In cases with missed abortion higher expression of GLUT1 and lower expression of GLUT3 in comparison with their expression in control group are c…
THE ROLE OF SIGNALING MOLECULES IN HUMAN THYMUS AND PINEAL GLAND AGEING
The work is devoted to the study of the expression of the signaling molecules involved in apoptosis, proliferation, extracellular matrix remodeling and the formation of immune status of the pineal and thymus glands. In the pineal and thymus glands in people ov…
COMPUTED TOMOGRAPHIC AND MORPHOLOGICAL COMPARISONSIN HEPATOCELLULAR CARCINOMA AT VARIOUS GRADES OF DIFFERENTIATION
The Use of the technique of contrast enhancement in spiral computed tomography (SCT) allows us to study the peculiarities of hemodynamics in the tumor tissue and thus facilitates the differential diagnosis. Сomparison of SKT data with the results of morphologi…
ANALYSIS OF THE VALUE OF DUAL USE TECHNOLOGIESIN MODERN CONSIDERATION OF BIOLOGICAL SAFETY PROBLEMS
The review discusses the biosafety issues related to the rapid development of molecular medicine and biotechnology. On an example of the USA data on efficiency of the accepted legislative base on restriction of dual use technologies, and also efficiency of the…
CLINICAL VALUE OF BONE REMODELING MARKERSIN BREAST CANCER PATIENTSWITH SKELETAL METASTASES
The dependence of biochemical markers of bone resorption (C-terminal telopeptide of type I collagen – b-CTx, deoxypyridinoline – DPID, tartrate-resistant acid phosphatase (TRAP) 5b) and osteosynthesis (bone alkaline phosphatase – BALP) on clinical manifestatio…
ASSOCIATION OF POLYMORPHIC MARKERS OF XENOBIOTIC BIOTRANSFORMATION GENESWITH BREAST CANCER IN FEMALES IN MOSCOW REGION
The association of +/– polymorphic markers of GSTM1 and GSTT1 genes and Ile105Val polymorphic marker of GSTP1 gene with the risk of development of breast cancer (BC) and its histological subtypes was studied. We have showed an association of null genotypes of …
MICROFLUIDICS AND ITS PERSPECTIVES IN MEDICINE
Microfluidics can raise our sights in the biomedical area. This paper presents an overview of microfluidic systems (IFS), which is evidence of the urgency of this trend. The concept of development of the microfluidic system (MFS) and the technology of producti…
SIGNALING MOLECULES: THE PLACE AND THE ROLE IN PERSONALIZED DIAGNOSTICS,TREATMENT AND PREVENTION OF SOCIALLY SIGNIFICANT DISEASES
This review is devoted to availability of investigation of expression of signaling molecules in personalized and predictive medicine. As exemplified in cardio-vascular pathology (hypertonic disease, myocardial infarction), Alzheimer’s disease and chronic obstr…