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Molecular Medicine Peer-reviewed scientific journal

Molecular Medicine

ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

PROTECTIVE IMPACT OF BIOREGULATOR PEPTIDES BY EFFECT OF CONSTANT GEOMAGNETIC FIELD ON ORGANOTYPIC TISSUE CULTURE OF VARIOUS GENESIS

Introduction. The investigations of the magnetic-biological effects are actual because the modern technical works are related to the constant magnetic field (CGF) Purpose of the study was the investigation of impact of (CMF) on the tissues of various genesis –…

10.29296/24999490-2020-02-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

STRUCTURALLY FUNCTIONAL ORGANIZATION OF THE GENOME OF A CLINICALLY SIGNIFICANT STRAIN HELICOBACTER PYLORI HP42K ISOLATED FROM THE PATIENT A HOSPITAL IN THE BELARUS REPUBLIC

Introduction. The use of genomic approaches allows a detailed studying of the pathogenetic potential of H. pylori bacteria. The aim of the study. To investigate the genome structural and functional organization of the H. pylori isolated in the Republic of Bela…

10.29296/24999490-2020-02-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

IMMUNOHISTOCHEMICAL STUDY OF TRANSCRIPTION FACTORS NEUROD1, PROX1, FOXM1, SOMATOSTATIN, AND CXCR4 RECEPTORS, CD38 IN GLIOBLASTOMAS TO DEVELOP NEW APPROACHES FOR THE TARGETED THERAPY

Currently, glioblastoma is an extremely malignant tumor, for which treatment only temozolomide is relatively effective. Aim to study the expression and variants of coexpression of transcription factors NeuroD1, Prox1, FoxM1, somatostatin receptors of the 2nd a…

10.29296/24999490-2020-02-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

THE STATE OF THE PROTEOLYSIS SYSTEM IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA ON THE BACKGROUND OF DIABETES MELLITUS TYPE 2

Introduction. The progression of inflammation in community-acquired pneumonia is associated with the activation of proteolytic enzymes, involved in eliminating the pathogenic agent, removing damaged structures. Proteinases are controlled by α1-proteinase inhib…

10.29296/24999490-2020-02-11Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

ANALYSIS OF HERMINAL MUTATIONS IN ONCOGENES AND TUMOR SUPPRESSOR GENES IN WOMEN WITH MULTIPLE PRIMARY MALIGNANT NEOPLASMS

Introduction. Multiple primary malignant neoplasms (MPMN) most often develop in individuals with a hereditary predisposition to oncological diseases. There are inherited allelic variants of oncogenes, tumor suppressor genes and their combinations which disrupt…

10.29296/24999490-2020-02-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

THE LEVEL OF EXPRESSION OF PROGESTERONE, ESTRADIOL AND VITAMIN D RECEPTORS IN MONONUCLEAR CELLS OF THE PERIPHERAL BLOOD OF PATIENTS WITH SURGICAL MENOPAUSE

Introduction. Patients with surgical menopause are at risk for an osteopenic syndrome. For adequate medical correction of osteoporosis, it is necessary to clarify the mechanisms of the pathogenesis of this condition. It is known that osteoclasts, the activatio…

10.29296/24999490-2019-01-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

THE LEVEL OF EXPRESSION OF PROGESTERONE, ESTRADIOL AND VITAMIN D RECEPTORS IN MONONUCLEAR CELLS OF THE PERIPHERAL BLOOD OF PATIENTS WITH SURGICAL MENOPAUSE

Introduction. Patients with surgical menopause are at risk for an osteopenic syndrome. For adequate medical correction of osteoporosis, it is necessary to clarify the mechanisms of the pathogenesis of this condition. It is known that osteoclasts, the activatio…

10.29296/24999490-2020-01-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

LIVER ALVEOCOCCOSIS: ULTRASOUND AND MORPHOLOGICAL COMPARISONS

Introduction. Alveococcosis is a parasitic disease associated with the formation of the liver tumor-like lesion. This parasitic tumor has infiltrative growth and the ability to metastasize, that is, it exhibits the properties of malignant tumors. The disease i…

10.29296/24999490-2020-01-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

EFFECT OF SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME ON THE COURSE OF BRONCHIAL ASTHMA

Aim. The work was carried out to study the role and features of small intestine bacterial overgrowth (SIBO) in the pathogenesis of bronchial asthma (BA). Material and methods. 80 BA patients were included in the study. SIBO was detected by the hydrogen breath …

10.29296/24999490-2020-01-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

IMMUNOHISTOCHEMICAL STUDY OF NEUROD1, NKX2.2, ISL1 TRANSCRIPTION FACTORS, SOMATOSTATIN AND CHROMOGRANIN A IN DIFFERENT FORMS OF CONGENITAL HYPERINSULINISM

Objective: a morphological study of the transcription factors NeuroD1, Nkx2.2, Isl1; somatostatin and chromogranin A in various forms of CH The methods included immunohistochemistry examination with antibodies to NeuroD1, insulin, somatostatin, ChrA, Nkx2.2, I…

10.29296/24999490-2020-01-07Details ↗
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