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Molecular Medicine
Introduction. Uterine fibroids – a benign tumor, growing from immature muscle cells of the vascular wall of the uterus. It ranked first among the benign tumors of the genital organs, with one in ten suffers from gynecological patients with uterine myoma. The a…
Introduction. The current direction of modern medicine is the development of new methods for non-invasive diagnosis of neurodegenerative diseases, in particular, Parkinson's disease. The goal of the investigation was the comparative analysis of α-synuclein and…
Introduction. Determination of the role of genetic markers in the formation of individual susceptibility to the effects of harmful chemicals both opens up new possibilities for assessing the risk of occupational and production-related diseases and address prev…
Introduction. Ulcerative colitis is a chronic inflammatory disease. Misbalance in innate and adaptive immunity including cytokines plays a significant role in its pathogenesis. Objective. To determine levels of cytokine TGFβ1, 2, 3, and IL6 in blood of patient…
Introduction. Russian population of Mycobacterium tuberculosis includes both highly virulent and less virulent strains; the Ural genotype makes an example of the latters. The aim of study was investigation of the most significant synonymous and non-synonymous …
Introduction. Diabetes mellitus type 1 and type 2 are having a number similar etiological factors and certain resemblance in the mechanisms of the disease. Therefore it is important to try to estimate the role of common genetic component in the genesis and for…
Introduction. High rate of non-developing pregnancy in the structure of reproductive loss dictates the need to identify the etiological factors of this disease at different levels of organization of alive matter. The aim of the study. The search for associatio…
Introduction. The pathogenesis of inflammatory bowel disease is complex and multifactorial. Studies have led to the current concept that the T-helper cells are components of the adaptive immune response whereas Toll-like receptors, NOD-like-receptors, RIG-I-li…
Introduction. In IVF-cycles ≈70% of human oocytes have different morphological abnormalities (dysmorphisms). Embryos from dysmorhic oocytes may have delay in development due to mitochondrial dysfunction and disorders of energy accumulation in the cell. The aim…
Introduction. Diploid human fibroblasts lines (DHFL) are widely used in diagnostic virology and experimental studies. One of the directions of use DHFL in virology and immunology is to create on their basis of a test system for determining the activity of inte…