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Molecular Medicine
Introduction. Chronic heart failure is a multifactorial disease, an important role in the pathogenesis of which is played by disorders of the functions of mitochondria and energy metabolism in cardiomyocytes, as well as a significant contribution is made by ge…
Introduction. Bronchial asthma is an inflammatory disease manifested by various phenotypes. The most studied phenotype of asthma is allergic. Molecular allergodiagnostics of allergic diseases using microchips makes it possible to determine the molecular profil…
Introduction. Heat shock proteins (HSPs) are a group of highly prospective compounds that can be used in various branches of clinical medicine, such as neurology, pharmacology and oncology. Studying the content of these proteins in various parts of the brain o…
Introduction. Type 1 diabetes mellitus is a chronic autoimmune disease associated with severe complications of organs and systems, including complications of the course of dental diseases. Material and methods. Results of 55 patients with type 1 DM became the …
Introduction. The pathogenesis of infection of the central nervous system (CNS) with SARS-CoV2 and nervourological complications are still poorly understood, as well as the link of viral infection with the risk and the course of gliomas. The aim. Evaluating of…
Introduction. The interest in neutrophil extracellular traps (NETs) in various conditions, including pregnancy complications was increased over the last decade. Accompanied by gestational diabetes mellitus (GDM) hyperglycemia contributes to neutrophil’s activa…
Introduction. Bronchial asthma is a heterogeneous disease involving different phenotypes. The allergic phenotype is the most studied model of asthma. Identification of causally significant allergens by determining allergen-specific IgE is the key to precision …
Introduction. Up to 20% of tuberculosis patients suffer from malignant neoplasms. In this case, the combination of both diseases in the lung is a particular problem. More than 60% of patients cannot complete combination therapy due to drug-resistant MBT. The a…
Introduction. In present, the medical community continues to study the impact of coronavirus infection on various organs and systems of the body. Infection with the SARS-CoV-2 virus causes multifaceted pathological processes and, among other things, affects th…
Introduction. In clinical experiments with various pathologies leading to the activation of POL, it was found that one of the most important areas of correction of oxidative stress is the use of drugs with the properties of antioxidants and antihypoxants [6, 7…