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Molecular Medicine
Found: 32
Introduction. Chronic bronchitis is one of the socially significant diseases. Accordingly, a search of the new more effective and safe bronchoprotective drugs is the one of aims of molecular medicine. The aim of the study. The goal of our research was the inve…
The paper is devoted to the history of the discovery of a new class of signaling molecules – kisspeptins and analysis of current ideas on their biological role. KISS1 gene was first described in 1996 as a gene which prevents metastasis of tumor cells. In the f…
Introduction. In recent years among non-drug methods of treatment and rehabilitation of patients of elderly and senile age is a promising application of low-intensity millimeter waves as an important reserve of increasing the effectiveness of the complex thera…
Implantation is the key process for becoming pregnant. Failure of implantation in IVF cycles is one of the main problems of modern reproductology. Search for biomarkers and the determination of the best time and maximal endometrial receptivity for the implemen…
The article reviews modern data on the participation of signaling molecules in the pathogenesis of obesity. This review provides the detailed description of the functional morphology of adipose tissue as the major endocrine and immune organ. The imbalance in p…
The review is devoted to the role of some signaling molecules produced by neuroendocrine and immune cells of the gastrointestinal tract (GIT) in the pathogenesis of the diseases of the digestive system. Special attention is paid to the key signaling molecules …
Buccal epithelium (BE) is an easily accessible target for molecular diagnosis of various diseases, and non-invasive way to get it is possible. This review summarizes the results of studies indicating a change in the expression of various signaling molecules an…
This review is devoted to availability of investigation of expression of signaling molecules in personalized and predictive medicine. As exemplified in cardio-vascular pathology (hypertonic disease, myocardial infarction), Alzheimer’s disease and chronic obstr…
The work is devoted to the study of the expression of the signaling molecules involved in apoptosis, proliferation, extracellular matrix remodeling and the formation of immune status of the pineal and thymus glands. In the pineal and thymus glands in people ov…
The assessment of vascular endothelial growth factor (VEGF) and endotelial NO – synthase (eNOS) expression levels in placental tissue samples obtained from pregnant females with gestational diabetes mellitus (GDM) has been performed. The highest level of these…
This article discusses the current level of research on the molecular mechanisms of development and progression of chronic heart failure in elderly and senile age. Described contribute to the pathogenesis of diseases of various signaling molecules and subsyste…
Introduction. Oxidative stress and mitochondrial dysfunction are observed in virtually any disease associated with premature aging. Signaling molecules produced by mitochondria can act as specific targets for the action of pharmacological agents in order to re…